Aims and Scope

The Open Dermatology Journal is an open access online journal which publishes original research articles, reviews/mini-reviews, letters and guest edited thematic issues in all areas of experimental and clinical research in dermatology, skin disorders, cosmetic surgery, dermatitis, dermatopathology, dermatological surgery, immunodermatology, paediatric dermatology, teledermatology and reconstructive and cosmetic surgery.


The Open Dermatology Journal, a peer-reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality papers rapidly and freely available to researchers worldwide.


Recent Articles

Serum Vitamin D Levels at Different Stages of Acne Vulgaris Patients Treated with Isotretinoin: A Prospective Study

Mohammed Al-Dhubaibi, Ghadah Alhetheli, Adel Alsenaid, Ahmed Abd Elneam

Background:

Acne vulgaris is a common chronic inflammatory skin disorder of pilosebaceous units. Isotretinoin (13-cis retinoic acid) is the most effective multifunctional treatment for moderate-to-severe and nodulocystic acne. Vitamin D plays a role in the immune system, and its deficiency might contribute to the pathogenesis of acne.

Objective:

To investigate whether isotretinoin improves serum 25-hydroxyvitamin D levels in acne vulgaris patients.

Methods:

This prospective cohort study included 68 patients with acne vulgaris. Lipid profiles, liver function tests, and serum 25-hydroxyvitamin D [25 (OH) D] levels were measured at baseline and three months after starting isotretinoin treatment.

Results:

There was a significant increase in serum vitamin D levels three months after starting isotretinoin treatment in mild acne patients (P=0.0003).

Conclusion:

Vitamin D levels are altered in acne vulgaris. Isotretinoin therapy is associated with an increase in vitamin D levels, which was statistically significant in mild acne patients. Considering the role of vitamin D in acne, effective treatment with isotretinoin might highlight vitamin D as a possible target for acne therapy or as a biomarker for disease activity and remission.


February 23, 2021
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Editor's Choice

Pyoderma Gangrenosum of the Face: A Rare Presentation and a Rapid Resolution

Julia Shah, Lorie Gottwald, Ashley Sheskey, Craig Burkhart

Background:

Pyoderma Gangrenosum (PG) is a disorder of neutrophil chemotaxis that often affects the lower extremities of patients with concurrent autoimmune disorders.

Result and Discussion:

Resolution of lesions typically requires a minimum of six weeks of treatment with systemic steroids. We present a unique case of multifocal PG involving the hand and face that healed after ten days of treatment with oral prednisone.


June 14, 2018
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